β-Catenin Mouse mAb(13C6)

Key facts:

Catalog NO:	TDY088
Source :	Mouse
Type:	Monoclonal
Application:	WB,IHC
Reactivity:	H,M,R
Isotype:	IgG1
MW(KDa):	92
Alternative Names:	CTNNB antibody, Cadherin associated protein antibody, b-catenin antibody

Specifications:

Source

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

Specificity

The β-Catenin mouse monoclonal antibody can detect endogenous β-Catenin proteins.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB 1:1,000 IHC 1:200

(Optimal dilutions should be determined by the end user)

Background:

The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.

Applications:

Western Blot

Western blot analysis of 1) Hela, 2) 293T, 3) MCF7, 4)Mouse Brain tissue ,3) Rat LiverTissue with β-Catenin mAb diluted at 1:2,000.

Immunohistochemistry

IHC staining of human breast cancer tissue with β-Catenin mouse mAb(13C6) diluted at 1:200.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".