Source

Synthesized peptide derived from human RIR2 AA range: 260-310

 

Specificity

This antibody detects endogenous levels of human RIR2

 

Storage

Store at -20°C. Stable for one year from the date of shipment.

 

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

 

Dilutions

WB 1:1000-2,000 (Optimal dilutions should be determined by the end user)

The ribonucleotide reductase enzyme facilitates the critical function of DNA replication and repair. RRM2 forms a complex with RRM1 the large subunit necessary for enzyme activity. This complex regulates the balance of deoxyribonucleotide pools necessary for DNA synthesis. Variations or dysregulations in the activity of RRM2 can influence genetic stability and cell proliferation emphasizing its importance in cellular function.