S2P Rabbit pAb

Key facts:

Catalog NO:	TT4205
Source :	Rabbit
Type:	Polyclonal
Application:	WB,IP,IF,ELISA
Reactivity:	H,M,R
Isotype:	IgG
MW(KDa):	57
Alternative Names:	MBTPS2 ; S2P ; Membrane-bound transcription factor site-2 protease ; Endopeptidase S2P ; Sterol regulatory element-binding proteins intramembrane protease ; SREBPs intramembrane protease

Specifications:

Source

The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350

Specificity

S2P Polyclonal Antibody detects endogenous levels of S2P protein.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB 1:500-2,000; IF 1:200-1000; ELISA 1:20,000

(Optimal dilutions should be determined by the end user)

Background:

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response

Applications:

Immunohistochemistry

Immunofluorescence analysis of A549 cells, using MBTPS2 Antibody. Thepicture on the right is blocked with the synthesized peptide.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".