METTL3 Rabbit pAb

Key facts:

Catalog NO:	TDY1122
Source :	Rabbit
Type:	Polyclonal
Application:	WB
Reactivity:	H,M,R
Isotype:	IgG
MW(KDa):	40-50
Alternative Names:	IME4,M6A,MT-A70,Methyltransferase like protein 3

Specifications:

Source

A Rabbit Polyclonal antibody is prepared by immunizing recombinant protein.

Specificity

Antibody can detects endogenous METTL3 protein.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB 1:2,000-5,000;

(Optimal dilutions should be determined by the end user)

Background:

The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N6 position of some RNAs and regulates various processes such as the circadian clock, differentiation of embryonic and hematopoietic stem cells, cortical neurogenesis, response to DNA damage, differentiation of T-cells and primary miRNA processing (PubMed:22575960, PubMed:24284625, PubMed:25719671, PubMed:25799998, PubMed:26321680, PubMed:26593424, PubMed:27281194, PubMed:27373337, PubMed:27627798, PubMed:28297716, PubMed:29348140, PubMed:29506078, PubMed:30428350, PubMed:9409616).

Applications:

Western Blot

Western blot analysis of 1)293T Cell, 2) 3T3 Cell, 3）Rat Liver Tissue Lysate using METTL3（TDY1122）Rabbit Polyclonal Antibody diluted at 1:2,000.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".