METTL14 Rabbit pAb

Key facts:

Catalog NO:	TDY1121
Source :	Rabbit
Type:	Polyclonal
Application:	WB
Reactivity:	H,M,R
Isotype:	IgG
MW(KDa):	60
Alternative Names:	KIAA1627，Methyltransferase like 14

Specifications:

Source

Rabbit Polyclonal antibody is prepared by immunizing Recombinant Protein.

Specificity

Antibody can detects endogenous METTL14 protein.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB: 1:2,000-5,000

(Optimal dilutions should be determined by the end user)

Background:

The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N6 position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis (PubMed:24316715, PubMed:24407421, PubMed:25719671, PubMed:27281194, PubMed:27373337, PubMed:29348140). In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core (PubMed:27281194, PubMed:27373337, PubMed:27627798, PubMed:29348140).

Applications:

Western Blot

Western blot analysis of 1)293T Cell, 2) 3T3 Cell, 3）Rat Brain Tissue Lysate using METTL14（TDY1121）Rabbit Polyclonal Antibody diluted at 1:2,000.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".