RanBP3 Mouse Monoclonal Antibody(7H8)

Key facts:

Catalog NO:	TDY1113
Source :	Mouse
Type:	Monoclonal
Application:	WB
Reactivity:	H,M,R
Isotype:	IgG1
MW(KDa):	70,90
Alternative Names:	DKFZp58611520，RANB3

Specifications:

Source

Mouse Monoclonal antibody is prepared by immunizing Recombinant Protein.

Specificity

Antibody can detects endogenous RanBP3 protein.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB: 1:1,000-2,000

(Optimal dilutions should be determined by the end user)

Background:

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

Applications:

Western Blot

Western blot analysis of 1)Hela Cell, 2) 3T3 Cell, 3) Rat Brain Tissue Lysate using RanbP3（TDY1113）Mouse Monoclonal Antibody diluted at 1:2,000.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".