PKR Rabbit pAb

Key facts:

Catalog NO:	TDYT3779
Source :	Rabbit
Type:	Polyclonal
Application:	WB,IHC,IF,ELISA
Reactivity:	H,M,R
Isotype:	IgG
MW(KDa):	74
Alternative Names:	EIF2AK2 ; PKR ; PRKR ; Interferon-induced ; double-stranded RNA-activated protein kinase ; Eukaryotic translation initiation factor 2-alpha kinase 2 ; eIF-2A protein kinase 2 ; Interferon-inducible RNA-dependent protein kinase ; P1/eIF-2A protein k

Specifications:

Source

The antiserum was produced against synthesized peptide derived from human PKR. AA range:413-462

Specificity

PKR Polyclonal Antibody detects endogenous levels of PKR protein.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB 1:500-2,000; IHC 1:100-300; IF 1:50-200; ELISA 1:20,000

(Optimal dilutions should be determined by the end user)

Background:

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Applications:

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".