GSDMD N-terminal (PTR1398) Mouse mAb

Key facts:

Catalog NO:	TDYM4266
Source :	Mouse
Type:	Monoclonal
Application:	WB,IF,ELISA
Reactivity:	H,M,R
Isotype:	IgG1,kappa
MW(KDa):	53,31
Alternative Names:	Gsdmdc1, Gsdmd, Gasdermin-D, Gasdermin domain-containing protein 1

Specifications:

Source

AA range: 1-100

Specificity

This antibody detects endogenous levels of GSDMD protein.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB 1:500-2,000; IF 1:100-500; ELISA 1:1,000-5,000

(Optimal dilutions should be determined by the end user)

Background:

GSDMD also known as gasdermin D is a protein known for its role in pyroptosis a form of programmed cell death. Its molecular weight is approximately 53 kDa. Mechanically GSDMD operates by forming pores in cell membranes. These pores disrupt cellular homeostasis and eventually lead to cell lysis. GSDMD is mainly expressed in immune cells including macrophages and neutrophils. Researchers frequently use GSDMD Western blot and GSDMD ELISA for its detection and quantification in various studies.

Applications:

Western Blot

Lane 1: U2OS Lane 2: THP-1 Lane 3: Mouse brain Lane 4: Rat womb Predicted band size: 53,31kDa Observed band size: 53,31kDa

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".