TFE3 Mouse mAb(8B4)

Key facts:

Catalog NO:	TDY798
Source :	Mouse
Type:	Monoclonal
Application:	IHC
Reactivity:	H
Isotype:	IgG1
MW(KDa):	62KD
Alternative Names:	BHLHE33; Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33

Specifications:

Source

Mouse Monoclonal antibody is prepared by immunizing Recombinant Protein.

Specificity

The TFE3 Mouse Monoclonal antibody can recognize recombinant and endogenous TFE3 proteins .

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

IHC 1:100-200

(Optimal dilutions should be determined by the end user)

Background:

transcription factor binding to IGHM enhancer 3(TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes.

Applications:

IHC	Immunohistochemical analysis of paraffin-embedded Human Esophageal Squamous Cell Carcinoma Tissue using TFE3 （TDY798）Mouse mAb diluted at 1:200.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".