P63-α Mouse mAb(10H5)

Key facts:

Catalog NO:	TDY774
Source :	Mouse
Type:	Monoclonal
Application:	WB,IHC
Reactivity:	H,R,M
Isotype:	IgG1
MW(KDa):	50-80
Alternative Names:	p63, Tumor protein 63 antibody,p53CP

Specifications:

Source

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

Specificity

The P63-α mouse monoclonal antibody can detect endogenous P63-α proteins.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

WB 1:1,000-2,000 IHC 1:100-200

(Optimal dilutions should be determined by the end user)

Background:

p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .

Applications:

Western Blot

Western blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α（TDY774）Mouse mAb diluted at 1:2000.

IHC

Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（TDY774）Mouse mAb diluted at 1:200.

IHC

Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（TDY774）Mouse mAb diluted at 1:200

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".