Acetyl NF kB P65（K314/K315) Mouse mAb(5G11)

Key facts:

Catalog NO:	TDY723
Source :	Mouse
Type:	Monoclonal
Application:	IHC
Reactivity:	H,R,M
Isotype:	IgG1
MW(KDa):	65
Alternative Names:	NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65

Specifications:

Source

Mouse Monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

Specificity

The Acetyl NF kB P65(K314/K315) Mouse Monoclonal Antibody can detects endogenous Acetyl NF kB P65(K314/K315) proteins.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

IHC 1:100-200

(Optimal dilutions should be determined by the end user)

Background:

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.

Applications:

IHC

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Acetyl NF kB P65(K314/K315) （TDY723）Mouse mAb diluted at 1:200.

IHC

Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Acetyl NF kB P65(K314/K315) （TDY723）Mouse mAb diluted at 1:200.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".