MLKL(Phospho Ser358) Mouse mAb(6B4)

Key facts:

Catalog NO:	TDY639
Source :	Mouse
Type:	Monoclonal
Application:	IHC
Reactivity:	H
Isotype:	IgG1
MW(KDa):	54
Alternative Names:	Mixed lineage kinase domain like protein, FLJ34389

Specifications:

Source

Mouse Monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

Specificity

The MLKL(Phospho Ser358) Mouse Monoclonal antibody can recognize endogenous Phospho ser358 MLKL proteins.

Storage

Store at -20°C. Stable for one year from the date of shipment.

Concentration

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Dilutions

IHC 1:100-200

(Optimal dilutions should be determined by the end user)

Background:

Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.

Applications:

IHC	Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-MLKL S358（ TDY639）Mouse mAb diluted at 1:200.

IHC	Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Phospho-MLKL S358（ TDY639）Mouse mAb diluted at 1:200.

Contact information:

Company:	BEI JING TDY BIOTECH CO.,LTD.
Orders:	TDYbiotech@163.com
Website:	http://www.tdybio.com
Telephone:	010-80117836
Address:	Zhen Xin Road 36.Changping Distict,Beijing

Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig

Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation

Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".