| Catalog NO: | TDY318 |
| Source : | Rabbit |
| Type: | Polyclonal |
| Application: | WB, IHC |
| Reactivity: | H, R, M |
| Isotype: | IgG |
| MW(KDa): | 92 |
| Alternative Names: | beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082 |
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The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
| Western Blot |
Western blot analysis of 1) 3T3, 2)Rat Liver, with β-Catenin Rabbit pAb TDY318 diluted at 1:2,000. |
| IHC |
Immunohistochemical analysis of paraffin-embedded human breast caricnoma using β-catenin(TDY318)Rabbit pAb diluted at 1:500. |
| Company: | BEI JING TDY BIOTECH CO.,LTD. |
| Orders: | TDYbiotech@163.com |
| Website: | http://www.tdybio.com |
| Telephone: | 010-80117836 |
| Address: | Zhen Xin Road 36.Changping Distict,Beijing |