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β-Catenin Rabbit pAb
Key facts:
Catalog NO:TDY318
Source :Rabbit
Type:Polyclonal
Application:WB, IHC
Reactivity:H, R, M
Isotype:IgG
MW(KDa):92
Alternative Names:beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082
Specifications:

Source

A Rabbit Polyclonal antibody is prepared by immunizing recombinant protein.


Specificity

The β-Catenin Rabbit Polyclonal antibody can detect endogenous β-Catenin proteins.


 
Storage

Store at -20°C. Stable for one year from the date of shipment.


 
Concentration

Immunogen Affinity Purified Rabbit IgG, 1mg/ml in PBS pH7.4, containing 0.02% sodium azide and 50% glycerol.



Dilutions

WB 1:1,000  IHC 1:500-1,000

(Optimal dilutions should be determined by the end user)

 

 

Background:

 

The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.

Applications:

Western Blot

 

Western blot analysis of 1) 3T3, 2)Rat Liver, with β-Catenin Rabbit pAb TDY318 diluted at 1:2,000.

IHC

 

Immunohistochemical analysis of paraffin-embedded human breast caricnoma using β-cateninTDY318Rabbit pAb diluted at 1:500.

Contact information:
Company:BEI JING TDY BIOTECH CO.,LTD.
Orders:TDYbiotech@163.com
Website:http://www.tdybio.com
Telephone:010-80117836
Address:Zhen Xin Road 36.Changping Distict,Beijing
Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig
Applications: WB-Western blot IHC-Immunochemistry IF-Immunofluorescence IP-Immunoprecipitation ChIP-Chormatin Immunoprecipitation
Please note: All products are"FOR RESEARCH USE ONLY.NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES".