| Cat#: TT2524 | Source#: Rabbit | Type#: Polyclonal | |
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| Applications: IHC, IF, ELISA |
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Reactivity: H,M |
| MW.(KDa): 343 |
Isotype: IgG |
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| Laminin , an extracellular protein , is a major component of the basement membrane. It is thought to mediate the attachment , migration , and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits , alpha , beta , and gamma , which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain , which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin) . Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. |
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| Immunohistochemistry |

Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using LAMA2 Antibody. The picture on the right is blocked with the synthesized peptide.
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| IF |

Immunofluorescence analysis of NIH/3T3 cells, using LAMA2 Antibody. The picture on the right is blocked with the synthesized peptide.
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| Source |
The antiserum was produced against synthesized peptide derived from human LAMA2. AA range:2011-2060 |
| Specificity |
Laminin α-2 Polyclonal Antibody detects endogenous levels of Laminin α-2 protein. |
| Storage |
Store at -20°C. Stable for one year. |
| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
IHC 1:100-300; IF 1:200-1000; ELISA 1:20,000
(Optimal dilutions should be determined by the end user)
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| LAMA2 ; LAMM ; Laminin subunit alpha-2 ; Laminin M chain ; Laminin-12 subunit alpha ; Laminin-2 subunit alpha ; Laminin-4 subunit alpha ; Merosin heavy chain |
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| Size: |
50μL ¥1000 100μL ¥1800 |
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| New Product: |
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