| Cat#： TP0270 | Source#： Rabbit | Type#： Polyclonal | |
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| Applications: WB,IF,ELISA,IHC |
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Reactivity: H,M,R |
| MW.(KDa): 145kd or 92kd(with limited samples) |
Isotype: IgG |
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| This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that , upon neurotrophin binding , phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. |
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| Western Blot |
Western Blot analysis of 293 cells using Phospho-Trk B (Y706) Polyclonal Antibody diluted at 1:1000
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| Western Blot |
Western blot analysis of lysates from mouse kidney, using Trk B (Phospho-Tyr705) Antibody. The lane on the right is blocked with the phospho peptide.
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| Immunohistochemistry |
Immunohistochemistry analysis of paraffin-embedded human brain, using Trk B (Phospho-Tyr705) Antibody. The picture on the right is blocked with the phospho peptide.
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| IF |
Immunofluorescence analysis of Hela cell. 1,Trk B (phospho Tyr706) Polyclonal Antibody (green) was diluted at 1:200 (4℃ overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog:RS3211 was diluted at 1:1000 (room temperature, 50min). 3 DAPI (blue) 10min.
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| Source |
The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr705. AA range:671-720 |
| Specificity |
Phospho-Trk B (Y706) Polyclonal Antibody detects endogenous levels of Trk B protein only when phosphorylated at Y706.The name of modified sites may be influenced by many factors |
| Storage |
Store at -20°C. Stable for one year. |
| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Dilutions |
WB 1:500-2,000; IHC 1:100-300; IF 1:200-1000; ELISA 1:20,000
(Optimal dilutions should be determined by the end user)
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| NTRK2 ; TRKB ; BDNF/NT-3 growth factors receptor ; GP145-TrkB ; Trk-B ; Neurotrophic tyrosine kinase receptor type 2 ; TrkB tyrosine kinase ; Tropomyosin-related kinase B |
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| Size: |
50μL ￥1000
100μL ￥1800 |
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| New Product: |
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| 直接下单: |
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立即下单
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