| Cat#: TM0259 | Source#: Mouse | Type#: Monoclonal | |
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| Applications: WB,IF,ELISA,IHC |
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Reactivity: H,M |
| MW.(KDa): 119 |
Isotype: IgG |
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| protein tyrosine kinase 2(PTK2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined |
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| Western Blot |

Western Blot analysis using FAK Monoclonal Antibody against A549 (1) and NIH/3T3 (2) cell lysate.:
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| Immunohistochemistry |

Immunohistochemistry analysis of paraffin-embedded cervices tumour with DAB staining using FAK Monoclonal Antibody.
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| IF |
Immunofluorescence analysis of B16 cells using FAK Monoclonal Antibody(green). Blue: DRAQ5 fluorescent DNA dye.
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| Source |
Purified recombinant fragment of human FAK expressed in E. Coli. |
| Specificity |
FAK Monoclonal Antibody detects endogenous levels of FAK protein. |
| Storage |
Store at -20°C. Stable for one year from the date of shipment. |
| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Dilutions |
WB 1:500-2,000; IHC 1:200-1,000; IF 1:200-1,000; ELISA 1:10,000
(Optimal dilutions should be determined by the end user)
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| PTK2 ; FAK ; FAK1 ; Focal adhesion kinase 1 ; FADK 1 ; Focal adhesion kinase-related nonkinase ; FRNK ; Protein phosphatase 1 regulatory subunit 71 ; PPP1R71 ; Protein-tyrosine kinase 2 ; p125FAK ; pp125FAK |
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| Size: |
50μL ¥1000 100μL ¥1800 |
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| New Product: |
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