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| CDO1 Rabbit pAb |
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| Cysteine dioxygenase type 1, Cysteine dioxygenase type I, CDO, CDO-I, CDO1 |
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| Cat#： TN2002 | Source#： Rabbit | Type#： Polyclonal | |
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| Applications: WB,ELISA |
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Reactivity: H,M,R |
| MW.(KDa): 27 |
Isotype: IgG |
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| atalytic activity:L-cysteine + O(2) = 3-sulfinoalanine.,cofactor:Binds 1 iron ion per subunit. Zinc to a much lesser extent.,cofactor:IRON; NAD(P)H.,function:Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.,induction:In hepatoblastoma HepG2 cells, down-regulated by phorbol 12-myristate 13-acetate.,pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.,PTM:The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen.,similarity:Belongs to the cysteine dioxygenase family.,subunit:Monomer.,tissue specificity:Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma HepG2 cells., |
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| Western Blot |
Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000
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| Source |
Synthesized peptide derived from part region of human protein |
| Specificity |
CDO1 Polyclonal Antibody detects endogenous levels of protein. |
| Storage |
Store at -20°C. Stable for one year from the date of shipment. |
| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Dilutions |
WB 1:500-2,000; ELISA 1:5,000-20,000
(Optimal dilutions should be determined by the end user)
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| Cysteine dioxygenase type 1, Cysteine dioxygenase type I, CDO, CDO-I, CDO1 |
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| Size: |
50μL ￥1000
100μL ￥1800 |
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| New Product: |
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| 直接下单: |
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立即下单
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