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SKI-1 Rabbit pAb
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MBTPS1 ; KIAA0091 ; S1P ; SKI1 ; Membrane-bound transcription factor site-1 protease ; Endopeptidase S1P ; Subtilisin/
 
Cat#: TT4309   |   Source#: Rabbit   |   Type#: Polyclonal   |
Applications: WB,IHC,ELISA   Reactivity: H,M,R
MW.(KDa): 130 Isotype: IgG
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction
Applications Specifications Alternative Names
Western  Blot                              

Western blot analysis of lysates from HCT116 cells, primary antibody wasdiluted at 1:1000, 4°over night

Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded human Squamous cellcarcinoma of lung

 
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100μL ¥1800

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