| Cat#: TT5392 | Source#: Rabbit | Type#: Polyclonal | |
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| Applications: WB,IHC,IF,ELISA |
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Reactivity: H,M,R |
| MW.(KDa): 35 |
Isotype: IgG |
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| The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. |
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| Source |
The antiserum was produced against synthesized peptide derived from the Internal region of human CD38
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| Specificity |
CD38 Polyclonal Antibody detects endogenous levels of CD38 protein. |
| Storage |
Store at -20°C. Stable for one year from the date of shipment. |
| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Dilutions |
WB 1:500-2,000; IHC 1:100-300; IF 1:50-200; ELISA 1:20,000
(Optimal dilutions should be determined by the end user)
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| CD38 ; ADP-ribosyl cyclase 1 ; Cyclic ADP-ribose hydrolase 1 ; cADPr hydrolase 1 ; T10 ; CD38 |
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| Size: |
50μL ¥1000 100μL ¥1800 |
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| New Product: |
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