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SOCS-1 (9T15) Rabbit Monoclonal Antibody
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SOCS1;SSI1;TIP3;Suppressor of cytokine signaling 1;SOCS-1;JAK-binding protein;JAB;STAT-induced STAT inhibitor 1;SSI-1;
 
Cat#: TR9381   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA   Reactivity: Human
MW.(KDa): 22kDa Isotype: IgG, Kappa
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],
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  Size:
50μL ¥1300
100μL ¥2300

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