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WISP1 (2B5) Rabbit Monoclonal Antibody
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CCN4
 
Cat#: TR9370   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA   Reactivity: Mouse,Rat
MW.(KDa): 40-45kDa Isotype: IgG, Kappa
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly pr
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  Size:
50μL ¥1300
100μL ¥2300

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