| Cat#: TR9370 | Source#: Rabbit | Type#: Monoclonal | |
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| Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA |
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Reactivity: Mouse,Rat |
| MW.(KDa): 40-45kDa |
Isotype: IgG, Kappa |
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| This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly pr |
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| Size: |
50μL ¥1300 100μL ¥2300 |
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