| Cat#: TR9330 | Source#: Rabbit | Type#: Monoclonal | |
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| Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA |
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Reactivity: Human,Rat |
| MW.(KDa): 65kDa(mature form),80kDa(precursor) |
Isotype: IgG, Kappa |
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| cofactor:Calcium.,disease:Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant.,enzyme regulation:Inhibited by EGTA.,function:May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis.,PTM:The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme.,similarity:Belongs to the peptidase S8 family.,similarity:Contains 1 peptidase S8 domain.,subunit:The precursor protein but not the mature protein may form multimers.,tissue specificity:Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells., |
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| Proprotein convertase subtilisin/kexin type 9;Neural apoptosis-regulated convertase 1;NARC-1;Proprotein convertase 9;PC9;Subtilisin/kexin-like protease PC9;NARC1,PSEC0052 |
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| Size: |
50μL ¥1300 100μL ¥2300 |
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| New Product: |
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| 直接下单: |
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