| Cat#: TR9308 | Source#: Rabbit | Type#: Monoclonal | |
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| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA |
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Reactivity: Human |
| MW.(KDa): 55kDa |
Isotype: IgG, Kappa |
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| The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010], |
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| IRF4;MUM1;Interferon regulatory factor 4;IRF-4;Lymphocyte-specific interferon regulatory factor;LSIRF;Multiple myeloma oncogene 1;NF-EM5 |
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| Size: |
50μL ¥1300 100μL ¥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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