| Cat#： TR9190 | Source#： Rabbit | Type#： Monoclonal | |
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| Applications: WB,IF-P,IF-F,IF-ICC,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 130kDa |
Isotype: IgG, Kappa |
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| Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
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| HDAC5;KIAA0600;Histone deacetylase 5;HD5;Antigen NY-CO-9 |
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| Size: |
50μL ￥1300
100μL ￥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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