| Cat#： TR9188 | Source#： Rabbit | Type#： Monoclonal | |
 |
| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA |
|
Reactivity: Human,Mouse,Rat |
| MW.(KDa): 21kDa |
Isotype: IgG, Kappa |
|
| function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.,PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).,PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active.,similarity:Contains 1 EGF-like domain.,subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor., |
|
|
|
|
| Size: |
50μL ￥1300
100μL ￥2300 |
|
| New Product: |
|
|
|
| 直接下单: |
|
立即下单
|
|
