| Cat#： TR9119 | Source#： Rabbit | Type#： Monoclonal | |
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| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 68kDa |
Isotype: IgG, Kappa |
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| There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cog |
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| LIMK1;LIMK;LIM domain kinase 1;LIMK-1 |
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| Size: |
50μL ￥1300
100μL ￥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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