| Cat#： TR9070 | Source#： Rabbit | Type#： Monoclonal | |
 |
| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA |
|
Reactivity: Human |
| MW.(KDa): 28kDa |
Isotype: IgG, Kappa |
|
| The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008], |
|
| FADD;MORT1;GIG3;Protein FADD;FAS-associated death domain protein;FAS-associating death domain-containing protein;Growth-inhibiting gene 3 protein;Mediator of receptor induced toxicity |
| |
|
|
|
|
| Size: |
50μL ￥1300
100μL ￥2300 |
|
| New Product: |
|
|
|
| 直接下单: |
|
立即下单
|
|
