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Pim-1 (15Q6) Rabbit Monoclonal Antibody
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PIM1;Serine/threonine-protein kinase pim-1
 
Cat#: TR9020   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA   Reactivity: Human,Mouse
MW.(KDa): 34kDa Isotype: IgG, Kappa
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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