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HDAC3 (2V18) Rabbit Monoclonal Antibody
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HDAC3;Histone deacetylase 3;HD3;RPD3-2;SMAP45
 
Cat#: TR9004   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA   Reactivity: Human,Mouse,Rat
MW.(KDa): 49kDa Isotype: IgG, Kappa
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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