| Cat#： TR8901 | Source#： Rabbit | Type#： Monoclonal | |
 |
| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA |
|
Reactivity: Human,Mouse,Rat |
| MW.(KDa): 250kDa |
Isotype: IgG, Kappa |
|
| A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
|
| BCR;BCR1;D22S11;Breakpoint cluster region protein;Renal carcinoma antigen NY-REN-26 |
| |
|
|
|
|
| Size: |
50μL ￥1300
100μL ￥2300 |
|
| New Product: |
|
|
|
| 直接下单: |
|
立即下单
|
|
