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Perforin (12Z8) Rabbit Monoclonal Antibody
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Cytolysin;FLH2;HPLH2;Lymphocyte pore-forming protein;P1;PERF_HUMAN;perforin 1;pore forming protein;Perforin 1;Perforin
 
Cat#: TR8900   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA   Reactivity: Mouse,Rat
MW.(KDa): 62kDa Isotype: IgG, Kappa
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
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  Size:
50μL ¥1300
100μL ¥2300

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