| Cat#: TR8900 | Source#: Rabbit | Type#: Monoclonal | |
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| Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA |
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Reactivity: Mouse,Rat |
| MW.(KDa): 62kDa |
Isotype: IgG, Kappa |
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| The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008], |
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| Cytolysin;FLH2;HPLH2;Lymphocyte pore-forming protein;P1;PERF_HUMAN;perforin 1;pore forming protein;Perforin 1;Perforin-1;PFP;PGFL;PIGF;PIGF-2;PLGF;Pore forming protein;prf1;SHGC-10760 |
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| Size: |
50μL ¥1300 100μL ¥2300 |
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| New Product: |
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