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eIF4G (1N7) Rabbit Monoclonal Antibody
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EIF4G1;EIF4F;EIF4G;EIF4GI;Eukaryotic translation initiation factor 4 gamma 1;eIF-4-gamma 1;eIF-4G 1;eIF-4G1;p220
 
Cat#: TR8888   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA   Reactivity: Human,Mouse,Rat
MW.(KDa): 250kDa Isotype: IgG, Kappa
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010],
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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