| Cat#: TR8848 | Source#: Rabbit | Type#: Monoclonal | |
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| Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 300kDa |
Isotype: IgG, Kappa |
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| E1A binding protein p300(EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008], |
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| EP300;P300;Histone acetyltransferase p300;p300 HAT;E1A-associated protein p300 |
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| Size: |
50μL ¥1300 100μL ¥2300 |
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| New Product: |
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| 直接下单: |
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