| Cat#: TR8828 | Source#: Rabbit | Type#: Monoclonal | |
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| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 81kDa |
Isotype: IgG, Kappa |
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| This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
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| MRE11A;HNGS1;MRE11;Double-strand break repair protein MRE11A;Meiotic recombination 11 homolog 1;MRE11 homolog 1;Meiotic recombination 11 homolog A;MRE11 homolog A |
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| Size: |
50μL ¥1300 100μL ¥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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