| Cat#： TR8796 | Source#： Rabbit | Type#： Monoclonal | |
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| Applications: WB,IF-P,IF-F,IF-ICC,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 54kDa |
Isotype: IgG, Kappa |
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| This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015], |
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| Mixed lineage kinase domain-like protein |
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| Size: |
50μL ￥1300
100μL ￥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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