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SREBP-1 (17F4) Rabbit Monoclonal Antibody
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Sterol regulatory element-binding protein 1;SREBP-1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory
 
Cat#: TR8793   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA   Reactivity: Human,Mouse,Rat
MW.(KDa): 125kDa Isotype: IgG, Kappa
This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016],
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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