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JNK1/2/3 (Phospho Thr183/Thr183/Thr221) (15A12) Rabbit Monoclonal Antibody
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MAPK8;JNK1;PRKM8;SAPK1;SAPK1C;Mitogen-activated protein kinase 8;MAP kinase 8;MAPK 8;JNK-46;Stress-activated protein k
 
Cat#: TR8675   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IF-P,IF-F,IF-ICC,IP,ELISA   Reactivity: Human,Mouse,Rat
MW.(KDa): 46,54kDa Isotype: IgG, Kappa
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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