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| NLRP3 (2Z14) Rabbit Monoclonal Antibody |
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| NLRP3;C1orf7;CIAS1;NALP3;PYPAF1;NACHT, LRR and PYD domains-containing protein 3;Angiotensin/vasopressin receptor AII/A |
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| Cat#： TR8592 | Source#： Rabbit | Type#： Monoclonal | |
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| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,IP,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 115kDa |
Isotype: IgG, Kappa |
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| This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are s |
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| NLRP3;C1orf7;CIAS1;NALP3;PYPAF1;NACHT, LRR and PYD domains-containing protein 3;Angiotensin/vasopressin receptor AII/AVP-like;Caterpiller protein 1.1CLR1.1;Cold autoinflammatory syndrome 1 protein;Cryopyrin;PYRIN-containing APAF1-like protein 1 |
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| Size: |
50μL ￥1300
100μL ￥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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