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PERK (17X9) Rabbit Monoclonal Antibody
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EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Panc
 
Cat#: TR8173   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IF-P,IF-F,IF-ICC,ELISA   Reactivity: Human,Mouse,Rat
MW.(KDa): 140kDa Isotype: IgG, Kappa
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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