| Cat#: TR8105 | Source#: Rabbit | Type#: Monoclonal | |
 |
| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA |
|
Reactivity: Human,Mouse,Rat |
| MW.(KDa): 44kDa,13kDa |
Isotype: IgG, Kappa |
|
| This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic |
|
| Transforming growth factor beta-1 proprotein;Latency-associated peptide(LAP);Transforming growth factor beta-1(TGF-beta-1);Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3 (TGF-beta-3);TGFB3 |
| |
|
|
|
|
| Size: |
50μL ¥1300 100μL ¥2300 |
|
| New Product: |
|
|
|
| 直接下单: |
|
立即下单
|
|