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TGF β1/3 (18F10) Rabbit Monoclonal Antibody
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Transforming growth factor beta-1 proprotein;Latency-associated peptide(LAP);Transforming growth factor beta-1(TGF-bet
 
Cat#: TR8105   |   Source#: Rabbit   |   Type#: Monoclonal   |
Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA   Reactivity: Human,Mouse,Rat
MW.(KDa): 44kDa,13kDa Isotype: IgG, Kappa
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic
Applications Specifications Alternative Names
 
  Size:
50μL ¥1300
100μL ¥2300

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