| Cat#： TR8010 | Source#： Rabbit | Type#： Monoclonal | |
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| Applications: WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA |
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Reactivity: Human,Mouse,Rat |
| MW.(KDa): 88kDa |
Isotype: IgG, Kappa |
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| The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper |
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| Western Blot |
Western blot analysis of lysates from MCF7 cells, using STAT3 Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody was used to detect the antibody.
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| Immunohistochemistry |
Single-cell and spatial transcriptomic analyses revealing tumor microenvironment remodeling after neoadjuvant chemoimmunotherapy in non-small cell lung cancer. Mol Cancer 24, 111 (2025).
IHC-P, human Non-small cell lung cancer (NSCLC) tissue, primary antibodies against STAT3 (RM8010), STAT5 (RM0478), IL-2 (BD-PE0366), Beta Catenin (RM1224), TGF-beta (RM3267), E2F1 (RM4981).
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| Storage |
Store at -20°C. Stable for one year from the date of shipment.
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| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
IHC-P 1:100-1:500, WB 1:1000-1:5000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
(Optimal dilutions should be determined by the end user)
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| STAT3;APRF;Signal transducer and activator of transcription 3;Acute-phase response factor |
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| Size: |
50μL ￥1300
100μL ￥2300 |
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| New Product: |
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| 直接下单: |
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立即下单
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