| Cat#: TT6210 | Source#: Rabbit | Type#: Polyclonal | |
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| Applications: WB,IHC,IF |
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Reactivity: H,M,R |
| MW.(KDa): 113 |
Isotype: IgG |
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| This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
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| Western Blot |

Zhou, Li, et al. "Coptisine induces apoptosis in human hepatoma cellsthrough activating 67-kDa laminin receptor/cGMP signaling." Frontiers inpharmacology 9 (2018).
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| Western Blot |

Yao, Chong, et al. "Crocin induces autophagic apoptosis in hepatocellularcarcinoma by inhibiting Akt/mTOR activity." OncoTargets and therapy 11(2018): 2017.
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| Immunohistochemistry |

Immunohistochemical analysis of para?n-embedded human brain
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| Source |
Synthesized peptide derived from human PARP-1. AA range: 410-460
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| Specificity |
This antibody detects endogenous levels of human PARP-1
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| Storage |
Store at -20°C. Stable for one year from the date of shipment.
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| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
WB 1:500-2,000; IHC 1:50-200; IF 1:50-200
(Optimal dilutions should be determined by the end user)
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| Poly [ADP-ribose] polymerase 1 ; PARP-1 ; ADP-ribosyltransferase diphtheria toxin-like 1 ; ARTD1 ; ADP-ribosyltransferase 1 ; ADPRT 1 ; Poly[ADP-ribose] synthase 1 ; |
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| Size: |
50μL ¥1000 100μL ¥1800 |
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| New Product: |
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| 直接下单: |
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立即下单
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