| Cat#： TDY1121 | Source#： Rabbit | Type#： Polyclonal | |
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| Applications: WB |
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Reactivity: H,M,R |
| MW.(KDa): 60 |
Isotype: IgG |
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| The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N6 position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis (PubMed:24316715, PubMed:24407421, PubMed:25719671, PubMed:27281194, PubMed:27373337, PubMed:29348140).
In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core (PubMed:27281194, PubMed:27373337, PubMed:27627798, PubMed:29348140).
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| Western Blot |
Western blot analysis of 1)293T Cell, 2) 3T3 Cell, 3）Rat Brain Tissue Lysate using METTL14（TDY1121）Rabbit Polyclonal Antibody diluted at 1:2,000.
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| Source |
Rabbit Polyclonal antibody is prepared by immunizing Recombinant Protein.
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| Specificity |
Antibody can detects endogenous METTL14 protein.
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| Storage |
Store at -20°C. Stable for one year from the date of shipment.
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| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
WB: 1:2,000-5,000
(Optimal dilutions should be determined by the end user)
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| KIAA1627，Methyltransferase like 14 |
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| Size: |
50μL ￥1000
100μL ￥1800 |
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| New Product: |
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| 直接下单: |
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立即下单
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