| Cat#： TDYT5743 | Source#： Rabbit | Type#： Polyclonal | |
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| Applications: WB,IHC,IF,ELISA |
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Reactivity: H,M,R |
| MW.(KDa): 45 |
Isotype: IgG |
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| This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012], |
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| Source |
The antiserum was produced against synthesized peptide derived from the C-terminal region of human CASP1. AA range:350-400
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| Specificity |
Caspase-1 Polyclonal Antibody detects endogenous levels of Caspase-1
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| Storage |
Store at -20°C. Stable for one year from the date of shipment.
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| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
WB 1:500-2,000; IHC 1:50-300; IF 1:50-200; ELISA 1:10,000-20,000
(Optimal dilutions should be determined by the end user)
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| CASP1 ; IL1BC ; IL1BCE ; Caspase-1 ; CASP-1 ; Interleukin-1 beta convertase ; IL-1BC ; Interleukin-1 beta-converting enzyme ; ICE ; IL-1 beta-converting enzyme ; p45 . |
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| Size: |
50μL ￥1000
100μL ￥1800 |
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| New Product: |
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| 直接下单: |
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立即下单
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