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Acetyl NF kB P65(K314/K315) Mouse mAb(5G11)
📄 生成PDF
NF kappa B p65, NFKB3, p65, p65 NF kB, RELA, TF65, Transcription Factor p65
 
Cat#: TDY723   |   Source#: Mouse   |   Type#: Monoclonal   |
Applications: IHC   Reactivity: H,R,M
MW.(KDa): 65 Isotype: IgG1

Reactivity:    H-Human  R-Rat  M-Mouse  Mk-Monkey  Dg-Dog  Ch-Chicken  Hm-Hamster  Rb-Rabbit  Sh-Sheep  Pg-Pig

 

 NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.

Applications Specifications Alternative Names

 

IHC

 

 

     

 

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Acetyl NF kB P65(K314/K315) (TDY723Mouse mAb diluted at 1:200.

IHC

Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Acetyl NF kB P65(K314/K315) (TDY723Mouse mAb diluted at 1:200.

 
  Size:
TDY723C-50μL ¥1000
TDY723F-100μL ¥1800

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