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| MLKL(Phospho Ser358) Mouse mAb(6B4) |
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| Mixed lineage kinase domain like protein, FLJ34389 |
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| Cat#: TDY639 | Source#: Mouse | Type#: Monoclonal | |
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| Applications: IHC |
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Reactivity: H |
| MW.(KDa): 54 |
Isotype: IgG1 |
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Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358. |
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| IHC |
Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-MLKL S358( TDY639)Mouse mAb diluted at 1:200.
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| IHC |
Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Phospho-MLKL S358( TDY639)Mouse mAb diluted at 1:200.
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| Source |
Mouse Monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.
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| Specificity |
The MLKL(Phospho Ser358) Mouse Monoclonal antibody can recognize endogenous Phospho ser358 MLKL proteins.
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| Storage |
Store at -20°C. Stable for one year from the date of shipment.
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| Concentration |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
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| Dilutions |
IHC 1:100-200
(Optimal dilutions should be determined by the end user)
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Mixed lineage kinase domain like protein, FLJ34389 |
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| Size: |
TDY639C-50μL ¥1000 TDY639F-100μL ¥1800 |
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| New Product: |
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